Some patients from TCGA-BRCA were included as the training cohort. Significant differences in enrichment scores for immune cells were observed. Immune-related pathways were found in the functional analysis. FRG expression profiles and clinical data were downloaded from The Cancer Genome Atlas (TCGA) database and Gene Expression Omnibus (GEO).
Therefore, the prognostic value of ferroptosis-related genes (FRGs) in BC warrants further investigation. Ferroptosis, an iron-dependent newly discovered mode of cell death, can be induced by lenaltinib and plays an important role in the biological behaviors of BC. My computer has 8GB RAM and good processor and still takes a lot to generate charts and analysis.Breast cancer (BC) is the most commonly diagnosed cancer and second leading cause of cancer-related death in women worldwide. Also, dose-response curves deserve more information and details about real life examples as well.Ībout the software specifically, I would suggest to make it lighter, or develop a light version.
However, IC50 calculation tutorials could be improved adding real life examples with common absorbance or fluorescence experiments. GraphPad tutorial is good and very informative. Figures are amazing and you can easily add standard deviation, which is a must to in scientific publications. I've tried other software before and GraphPad is way easier to use and complete. It's pretty easy to import data and replicates and perform analysis over these replicates. That's an incredible advantage for people who's learning and selecting their "go-to" statistic software. GraphPad allows you to have one month free trial with all the features. It's an amazing software and it allowed me to transition from Excel and Origin and only use GraphPad now. I've also generated my charts, figures and reports directly to publish in peer-reviewed journals because of their quality. Comments: I have used GraphPad to calculate IC50, EC50 in fluorescence-based assays for my scientific project.
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